Home Allied Health Services Janeway’s Immunobiology (Immunobiology: The Immune System (Janeway)), 8th Edition, Kenneth Murphy

Janeway's Immunobiology (Immunobiology The Immune System (Janeway)), 8th Edition

Janeway’s Immunobiology is a textbook that introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.

Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout—that of the host’s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.

Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.

New in the Eighth Edition

  • Innate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook.  Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes).
  • The section on complement has been reworked and reconceived—explaining the lectin pathway first—making it easier to teach by placing it into the context of innate recognition.
  • Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms.
  • The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book.
  • Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen.
  • Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria.
  • Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways.
  • Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines.
  • Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text.
  • The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways.
  • New references have been added throughout the text.

I was heavily reliant on this book for an immunology course I took as an elective, and while I am impressed by the amount of research and effort that went into this textbook, I wasn’t impressed by the presentation of the content. Sure, this book is very detailed, and its scientific journal-like diction helped me a lot when it came down to reading scientific literature, but the material was written in a very convoluted way.

It seemed like this was meant for a group of students who were already versed in the topic of immunology,somewhat, and not for people who like me were new to the subject. In some chapters the book would begin talking about one system, move on another system and then loop back around to the first system. Chapter divisions were really nice and so were the summaries because it is very hard to skim over this text to review or look for pertinent information. Some information that took 3 pages to explain were was already evident in a preceding diagram, and could have been summarized onto a single page. I definitely learned a lot from reading the book and the illustrations were great, but I felt that getting through a 50 page chapter took a lot of caffeine and will power- that stuff is dense!

There are already many comments on the content, but I wanted to speak to the format of the Kindle Version. First and foremost, the Kindle version is a “print” format which means it will not work on the black-and-white Kindles — not even the new Kindle Paperwhite. It needs to render images so only the Kindle Fire series, PCs, MACs, and iPad are supported. I don’t know why the Android systems are not supported — it might be a licensing thing.

Even though this textbook is in “print” format, you will still be able to interact with the text — highlight words, phrases or sentences; use the dictionary; and even add bubble notes.

Zoomed all the way out, the Kindle version looks exactly like the print version. The added features are more like PDF files — you can do a search, copy text and paste from it, highlight, and as already mentioned, add notes (in a bubble style like in Adobe).

I bought the physical printed version and the Kindle version at the same time…after a few days pondering the pros/cons of print versus ebook, I returned the printed version, and committed to the Kindle version. Since I’m an Android tablet user, I’m tied to my home computer or laptop when I want to read, but this is no major inconvenience.

I have four graduate level classes this semester, and no physical textbooks. This is the lightest my backpack has ever been.

Product Details :

  • Series: Immunobiology: The Immune System (Janeway)
  • Paperback: 888 pages
  • Publisher: Garland Science; 8 edition (July 25, 2011)
  • Language: English
  • ISBN-10: 0815342438
  • ISBN-13: 978-0815342434
  • Product Dimensions: 1.3 x 8.1 x 10.6 inches

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